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What causes psoriasis
What causes psoriasis?
Research indicates that psoriasis may be a disorder of the immune system. The immune system includes a type of white blood cell, called a T cell, that normally helps protect the body against infection and disease. Scientists now think that psoriasis is related to an abnormal immune system that produces too many of the immune cells, called T cells, in the skin. These T cells trigger the inflammation and excessive skin cell reproduction seen in people with psoriasis. This leads to inflammation and flaking of skin.
In some cases, psoriasis is inherited. Researchers are studying large families affected by psoriasis to identify a gene or genes associated with the disease. (Genes govern every body function and determine inherited traits that are passed from parent to child.)
People with psoriasis may notice that there are times when their skin worsens, then improves. Conditions that may cause flare-ups include changes in climate, infections, stress, and dry skin. Also, certain medicines, such as the nonsteroidal antiinflammatory drug indomethacin and medicines used to treat high blood pressure or depression, may trigger an outbreak or worsen the disease
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